Nutraceutical, Cosmeceutical, and Pharmaceutical Preparations

SK-713™ is a clinically tested cutting-edge delivery technology composed of the charged delivery spheres that encapsulate and transport an active compound into the system. These spheres can enhance permeation and retention of the compound and may be used for oral, IV, and topical ingredients. SK-713™ has been the subject of several published studies and book chapters, and is unique in its ability to improve not only absorption of enveloped ingredients, but also to enhance surrounding tissue metabolism, thereby creating a novel and potent synergy.

The SK-713™ solution can transport very large molecules across surfaces membranes, can transport a suite of complementary ingredients simultaneously, and can extend the duration of activity of transported compounds in targeted tissues.

What Is It?

  • SK-713™ is a unique, proprietary delivery technology composed of delivery spheres shown to enhance active ingredient uptake and bioavailability
  • Produced using a highly specific process, which not only helps amplify the absorption and bioavailability of enveloped ingredients, but also provides direct benefit to the physiology
  • Technology can be augmented to match desired outcome of formula
  • May be applied to targeted portions of a formula, or the total compound
  • Direct benefits of SK-713™ also pass on to cells, or the actual target of the delivery technology
  • SK-713™ is very stable and possesses extensive shelf life
  • Ingredients treated with SK-713™ acquire better stability as well
  • Can be used in both ingestible and topical preparations
  • Effective with both water- and fat-soluble compounds, simultaneously
  • Able to envelope multiple nutrients within each transport sphere, creating maximum synergy
  • Benefits are both direct and indirect. SK-713™ enhances nutrient uptake and also delivers direct cholinergic and homeostatic benefits to cellular physiology

Absorption

“Whatever the nutritional potential of a food, its contribution is nonexistent if it does not pass the test of absorption. Those nutrients that have not been transferred through the intestinal mucosal cell to enter the circulation have, for all nutritional intent and purpose, have never been eaten. The variety of nutrients from the organism’s environment that have been made available Luminec Pharmaceuticals SK-713 by absorption must be transported through the circulatory system to the aqueous microenvironment of the cells. There, they serve their ultimate purpose: participation in the metabolic activities in the cells on which the life of the total organism depends.”

—Ruth L. Pike and Myrtle L. Brown, Nutrition: An Integrated Approach, John Wiley & Sons, 1984, p. 283

SK-713 ™ is customizable depending on desired effect of specific formulation

  • Technology can be augmented to match desired outcome of formula
  • May be applied to targeted portions of formula, or total compound
  • May be used on virtually any formula of an aqueous nature
  • May also be applied as a coating to powders, or added in dry form to other powders for reconstituting with liquids.
  • Coating of SK-713™ acts to increase solubility and uptake of dry powders
  • Direct benefits of SK-713™ also pass on to cells from dry powders (this technology is not available through any other known source)
  • SK-713™ is very stable and possesses extensive shelf life
  • Ingredients treated with SK-713™ acquire better stability as well

Surface Tension of SK-713™ Sphere vs. standard liposomal sphere

  • In independent clinical testing, both an SK-713™ TM Sphere and a standard liposomal sphere were measured for contact angle reflection of light, with the drop of compound on glass, a non-reactive surface. A higher contact angle signifies a higher surface tension.
  • The standard liposomal sphere demonstrated a contact angle of 39, while the SK 713™ Sphere contact angle was measured at 47.7.
  • The SK-713™ Sphere was shown to have a 22.3% greater degree of contact angle, thereby demonstrating a significantly greater degree of surface tension, all due to the unique production methods of SK-713™.